UPDATE 11.53AM: A Warwick teenager has become the second person to die on Darling Downs district roads this year.
Darling Downs district officer Inspector Mike Curtin said initial investigations indicated the 18-year-old's black Holden Commodore sedan was on the wrong side of the Cunningham Hwy when it and a B-double truck collided about 500m east of the Leslie Dam Rd intersection about 8.50pm yesterday.
Insp. Curtin said the truck was heading towards Warwick and the Commodore was heading west.
The teenager died at the scene.
Paramedics took the 51-year-old Victorian truck driver to Warwick Base Hospital where he was treated for minor injuries and shock.
He has since been discharged.
Emergency services had to divert traffic around the scene before it was cleared.
The tragedy came on the same night that a 34-year-old Lockyer Valley woman died from injuries sustained in a Warrego Hwy crash.
The Hatton Vale woman had been in Royal Brisbane Hospital after being flown from the scene of last Thursday's crash at Hatton Vale.
"We are just pleading with the public to proactively participate in safe driving practices so that we don't see a repetition of 2013 and 2014 which were horrific years for the Darling Downs district in terms of fatalities and lives lost," Inspector Curtin said.
There were 30 people who died in the region in 2013 and a further 23 lives lost last year.
Investigations into the Cunningham Hwy crash are continuing.
UPDATE: An 18-year-old man, and sole occupant of the car, was pronounced deceased at the scene and the 51-year-old male truck driver was transported to Warwick Hospital to be treated for shock.
The highway was closed for a number of hours, but has since re-opened.
The Forensic Crash Unit is investigating.
BREAKING: A man has been killed after a head on crash with a truck on the Cunningham Highway.
Emergency services received the call at 8.54 pm to attend the crash near the Leslie Dam turn off west of Warwick.
The road remains closed while crews clear the scene.
This is the first fatal accident on Southern Downs roads for 2015.
No further information is available at this stage.
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